Saturday, February 11, 2012

Nuclear cytokine-activated IKKalpha controls prostate cancer metastasis by repressing Maspin.


Nature. 2007 Apr 5;446(7136):690-4. Epub 2007 Mar 18.

Nuclear cytokine-activated IKKalpha controls prostate cancer metastasis by repressing Maspin.

Source

Laboratory of Gene Regulation and Signal Transduction, Department of Pharmacology and Cancer Center, School of Medicine, University of California, San Diego, 9500 Gilman Drive, La Jolla, California 92093-0723, USA.

Erratum in

  • Nature. 2009 Feb 12;457(7231):920.

It has come to our attention that some of the control lanes in Fig. 2a (Kai1 and Mkk4 control lanes) may 
have been inadvertently duplicated during figure assembly; 
the other control lanes and the experimental Maspin lanes are correct. 
We have therefore repeated the experiments and obtained the same results as those in the published figure. 
The primary data from this experiment can be found in Supplementary Information. 



どこが複製されている画像なのでしょうか?

1 comment:

  1. Maspin, a putative tumor suppressor that is down-regulated in breast and prostate cancer, has been associated with decreased cell motility. Snail transcription factor is a zinc finger protein that is increased in breast cancer and is associated with increased tumor motility and invasion by induction of epithelial-mesenchymal transition (EMT).
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