Saturday, February 11, 2012

The E3 ubiquitin ligase itch couples JNK activation to TNFalpha-induced cell death by inducing c-FLIP(L) turnover.


Cell. 2006 Feb 10;124(3):601-13.

The E3 ubiquitin ligase itch couples JNK activation to TNFalpha-induced cell death by inducing c-FLIP(L) turnover.


Division of Cancer Immunotherapeutics & Tumor Immunology, Beckman Research Institute at City of Hope, City of Hope National Medical Center, 1500 E. Duarte Road, KCRB 3009, Duarte, CA 91010, USA.

Source




Cells in Fig.3D look very similar to cells in Fig.4A, but they are supposed to be of different genotypes, and transfected and treated differently.
http://imgur.com/2A2CUHV




Source


In Fig. 1A, the 12.5 day WT and double mutant embryos are the same. See the identical light reflections. 

http://i.imgur.com/oEWRbgg.png


No comments:

Post a Comment